| Identification | Back Directory | [Name]
IQHNJQKWEMCXAD-YYZTVXDQSA-N | [CAS]
709026-60-8 | [Synonyms]
IQHNJQKWEMCXAD-YYZTVXDQSA-N
C16-Sphingosine-1-phosphate
Sphingosine-1-phosphate (d16:1) | [Molecular Formula]
C16H34NO5P | [MOL File]
709026-60-8.mol | [Molecular Weight]
351.42 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
0.3 M NaOH: 4 mg/ml; DMF: <50 μg/ml; DMSO: <50 μg/ml; PBS (pH 7.2): <50 μg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P; ) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma trabecular meshwork samples. | [Uses]
C16-Sphingosine-1-phosphate is an important regulator of a wide variety of biological processes acting as an endogenous ligand to EDG/S1P receptors. | [Definition]
ChEBI: Hexadecasphing-4-enine-1-phosphate is a sphingoid 1-phosphate that is hexadecasphing-4-enine substituted by a phospho group at position 1. It has a role as a mouse metabolite. It is functionally related to a hexadecasphing-4-enine. |
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