| Identification | Back Directory | [Name]
YUNACONITINE | [CAS]
70578-24-4 | [Synonyms]
Yunnaconitine
YUNACONITINE USP/EP/BP
Yunaconitine GuayewuanineB
11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine
Aconitane-3,8,13,14-tetrol,20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate14-(4-methoxybenzoate), (1a,3a,6a,14a,16b)-
Aconitane-3,8,13,14-tetrol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-(4-methoxybenzoate), (1α,3α,6α,14α,16β)- | [Molecular Formula]
C35H49NO11 | [MDL Number]
MFCD00880612 | [MOL File]
70578-24-4.mol | [Molecular Weight]
659.768 |
| Chemical Properties | Back Directory | [Melting point ]
142-144℃ | [Boiling point ]
722.8±60.0 °C(Predicted) | [density ]
1.34 | [solubility ]
DMF: 1 mg/ml; DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml | [form ]
A solid | [pka]
12.67±0.70(Predicted) | [color ]
White to off-white | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Yunnaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformat
ional changes. Yunnaconitine is a deiterpene alkaloid, known to exhibit cytotoxic activity in human leukemic cell. |
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