Identification | Back Directory | [Name]
DPBQ | [CAS]
7029-89-2 | [Synonyms]
DPBQ Benzo[g]quinoxaline-5,10-dione, 2,3-diphenyl- | [Molecular Formula]
C24H14N2O2 | [MDL Number]
MFCD30537543 | [MOL File]
7029-89-2.mol | [Molecular Weight]
362.38 |
Hazard Information | Back Directory | [Uses]
DPBQ activates p53 and triggers apoptosis in a polyploid-specific manner, but does not inhibit topoisomerase or bind DNA. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells[1]. | [storage]
Store at -20°C | [References]
[1] Choudhary A, et al. Identification of Selective Lead Compounds for Treatment of High-Ploidy Breast Cancer. Mol Cancer Ther. 2016;15(1):48-59. DOI:10.1158/1535-7163.MCT-15-0527 |
|
Company Name: |
cjbscvictory
|
Tel: |
13348960310 13348960310 |
Website: |
https://www.weikeqi-biotech.com/ |
|