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ChemicalBook--->CAS DataBase List--->697226-52-1

697226-52-1

697226-52-1 Structure

697226-52-1 Structure
IdentificationBack Directory
[Name]

N-TRICOSANOYLTRYPTAMINE
[CAS]

697226-52-1
[Synonyms]

TAT
MEC17
TAT-amide
ATAT1 human
N-TRICOSANOYLTRYPTAMINE
Tyrosine aminotransferase
TRICOSANOIC ACID TRYPTAMIDE
alpha tubulin acetyltransferase 1
N-[2-(3-INDOLYL)ETHYL]TRICOSANAMIDE
L-tyrosine:2-oxoglutarate aminotransferase
ANTI-TAT (CENTER) antibody produced in rabbit
TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG-NH2
H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2
[Molecular Formula]

C64H119N33O13
[MDL Number]

MFCD07366643
[MOL File]

697226-52-1.mol
[Molecular Weight]

1558.84
Chemical PropertiesBack Directory
[Melting point ]

116-120 °C
[density ]

1.54±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

Solid
[color ]

White to off-white
[biological source]

rabbit
Safety DataBack Directory
[WGK Germany ]

3
[F ]

10
Hazard InformationBack Directory
[Biological Activity]

ATAT1 (α tubulin acetyltransferase 1) catalyses the acetylation of lysine 40 of α-tubulin and microtubule. ATAT1 expression is essential for microtubule stabilization and mediates cilium formation. Upart from acetylationαTAT1 interacts with doublecortin (a microtubule associated protein) to degrade microtubules th at are not aligned with acetyltransferase activity. αTAT1 regulates the Wnt1 signalling pathway via β-catenin and promotes tumorigenesis. Overexpression of the ATAT1 gene is observed in colon cancer and is known to contribute to its progression.
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