| Identification | Back Directory | [Name]
Heptaethylene glycol di(p-toluenesulfonate) | [CAS]
69502-27-8 | [Synonyms]
Tos-PEG8-Tos
Bis-Tos-PEG7
Heptaethylene glycol di(p-toluenesulfonate)
3,6,9,12,15,18-Hexaoxaicosane-1,20-diyl bis(4-methylbenzenesulfonate)
3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol, 1,20-bis(4-methylbenzenesulfonate) | [Molecular Formula]
C28H42O12S2 | [MDL Number]
MFCD06292255 | [MOL File]
69502-27-8.mol | [Molecular Weight]
634.756 |
| Hazard Information | Back Directory | [Description]
Tos-PEG8-Tos is a PEG linker containing two tosyl groups. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. | [Uses]
Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|