| Identification | Back Directory | [Name]
Cyclicdimethylpolysiloxane | [CAS]
69430-24-6 | [Synonyms]
kf993
UP 1004
q2-1401
X 2-1401
sws03314
sws-f222
dowcorning344
Silwet FZ 2166
Silicone TSA 405A
dowcorningx2-1401
dowcorning344fluid
cyclosiloxanes,di-me
Cyclodimethylsiloxanes
Siloxanes, cyclic, di-Me
POLYDIMETHYLCYCLOSILOXANE
Cyclomethicone 6 (200 mg)
dimethylcyclopolysiloxane
cyclopolydimethylsiloxane
polydimethylsiloxycyclics
DMC Cyclodimethylsiloxanes
CYCLOMETHICONE 4 (200 MG)
Cyclicdimethylpolysiloxane
Cyclic polydimethylsiloxane
Dimethyl siloxane cyclics mixture
Cyclomethicone (pharmaceutical grade) | [EINECS(EC#)]
209-136-7 | [MDL Number]
MFCD01771102 |
| Hazard Information | Back Directory | [Chemical Properties]
Cyclomethicone occurs as a clear, colorless and tasteless volatile liquid. | [Uses]
Pharmaceutic aid (wetting agent). | [Production Methods]
Cyclomethicone is manufactured by the distillation of crude polydimethylsiloxanes. | [Brand name]
VS-7158
(Witco); VS-7207 (Witco); VS-7349 (Witco). | [Pharmaceutical Applications]
Cyclomethicone is mainly used in topical pharmaceutical and cosmetic formulations such as water-in-oil creams.
Cyclomethicone has been used in cosmetic formulations, at concentrations of 0.1-50%, since the late 1970s and is now the most widely used silicone in the cosmetics industry. Its high volatility, and mild solvent properties, make it ideal for use in topical formulations because its low heat of vaporization means that when applied to skin it has a ‘dry’ feel. | [Safety]
Cyclomethicone is generally regarded as a relatively nontoxic and nonirritant material. Although it has been used in oral pharmaceutical applications, cyclomethicone is mainly used in topical pharmaceutical formulations. It is also widely used in cosmetics. Studies of the animal and human toxicology of cyclomethicone suggest that it is nonirritant and not absorbed through the skin. Only small amounts are absorbed orally; an acute oral dose in rats produced no deaths. | [storage]
Cyclomethicone should be stored in an airtight container in a cool, dry, place. | [Toxics Screening Level]
The initial threshold screening level (ITSL) for cyclopolydimethylsiloxane 30 μg/m3 based on an annual averaging time. | [Regulatory Status]
Included in the FDA Inactive Ingredients Database(oral powderfor reconstitution, topical lotion, topical cream, topical emulsion). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
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