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ChemicalBook--->CAS DataBase List--->69123-94-0

69123-94-0

69123-94-0 Structure

69123-94-0 Structure
IdentificationBack Directory
[Name]

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
[CAS]

69123-94-0
[Synonyms]

FAU
2'-Deoxy-2'-fluoro-beta-D-arabinouridine
2'-Fluoro-2'-deoxy-arabinofuranosyl-uridine
2'-Fluoro-arabinofuranosyl-2'-deoxy-uridine
1,3-Dimethyl-4-Amino-5-Formamide-Uracil FAU
1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil
2’-fluoro-5-ethyl-1-beta-d-arabinofuranosyluracil
2'-FLUORO 2'-DEOXYURACIL-BETA-D-ARABINOFURANOSIDE
2'-FLUORO-2'-DEOXYURACYL-BETA-D-ARABINOFURANOSIDE
1-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)URACIL
1-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-uraci
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
2,4(1H,3H)-PyriMidinedione, 1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-
2,4(1H,3H)-PYRIMIDINEDIONE, 1-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)
1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
1-((2R,3S,4R,5R)-3-FLUORO-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDINE-2,4-DIONE
1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
[Molecular Formula]

C9H11FN2O5
[MDL Number]

MFCD00870798
[MOL File]

69123-94-0.mol
[Molecular Weight]

246.19
Chemical PropertiesBack Directory
[Appearance]

Colourless solid
[Melting point ]

162 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
[density ]

1.63±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[form ]

Solid
[pka]

9.39±0.10(Predicted)
[color ]

White to off-white
[CAS DataBase Reference]

69123-94-0
Hazard InformationBack Directory
[Chemical Properties]

Colourless solid
[Uses]

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302+H312+H332-H315-H319-H335-H340
[Precautionary statements ]

P260-P280-P301+P312
[HS Code ]

2934999090
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