| Identification | Back Directory | [Name]
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid | [CAS]
683808-78-8 | [Synonyms]
Poloppin
Poloppin >=98% (HPLC)
3-{5-(4-bromophenyl)-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-2-yl}propanoic acid | [Molecular Formula]
C20H15BrF3NO2 | [MDL Number]
MFCD03706653 | [MOL File]
683808-78-8.mol | [Molecular Weight]
438.238 |
| Chemical Properties | Back Directory | [Boiling point ]
536.7±50.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
powder | [pka]
4.62±0.10(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Description]
Poloppin is a modulator of protein-protein interactions of the mitotic polo-like kinases. It acts by targeting mutant KRAS, working synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells. |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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