| Identification | Back Directory | [Name]
7,8-DIHYDRO-L-BIOPTERIN | [CAS]
6779-87-9 | [Synonyms]
BH2
DIHYDROBIOPTERIN
7,8-dihydrobiopterin
7,8-DIHYDRO-L-BIOPTERIN
L-erythro-Dihydrobiopterin
L-erythro-7,8-Dihydrobiopterin
2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-1H-pteridin-4-one
2-Amino-6-(1,2-dihydroxy-propyl)-7,8-dihydro-3H-pteridin-4-one
2-AMINO-6-(1R,2S-DIHYDROXYPROPYL)-7,8-DIHYDRO-4(1H)-PTERIDINONE
4(1H)-pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-
2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone
2-aMino-6-((1S,2R)-1,2-dihydroxypropyl)-7,8-dihydropteridin-4(3H)-one | [Molecular Formula]
C9H13N5O3 | [MDL Number]
MFCD00049357 | [MOL File]
6779-87-9.mol | [Molecular Weight]
239.23 |
| Chemical Properties | Back Directory | [Appearance]
Yellow Powder | [Melting point ]
>300°C dec. | [Boiling point ]
470.8±55.0 °C(Predicted) | [density ]
1.88 | [storage temp. ]
−20°C
| [solubility ]
Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly), DMSO (Slightly), Me | [form ]
Solid | [pka]
10.47±0.20(Predicted) | [color ]
Pale Yellow to Brown | [BRN ]
536551 | [Stability:]
Hygroscopic | [InChIKey]
FEMXZDUTFRTWPE-AWFVSMACSA-N | [CAS DataBase Reference]
6779-87-9 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Powder | [Uses]
An oxidation producct of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of G | [Uses]
The reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.
| [Uses]
BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM. | [Description]
BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM.1 | [Definition]
ChEBI:L-erythro-7,8-dihydrobiopterin is a 7,8-dihydrobiopterin in which the 1,2-dihydroxypropyl group has (1R,2S)-configuration; naturally occurring form. It is an enantiomer of a D-erythro-7,8-dihydrobiopterin. | [storage]
Store at -20°C | [References]
[1] shen r, alam a, zhang y. inhibition of gtp cyclohydrolase i by pterins[j]. biochimica et biophysica acta (bba)-general subjects, 1988, 965(1): 9-15.
[2] sugiyama t, levy b d, michel t. tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells[j]. journal of biological chemistry, 2009, 284(19): 12691-12700. |
|
|