Identification | Back Directory | [Name]
DIDS | [CAS]
67483-13-0 | [Synonyms]
DIDS DIDS,90% DIDS DISODIUM SALT DIDS (sodium salt) Hydrate [Protein Modification Reagent] 4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID, 2NA DISODIUM 4,4'-DIISOTHIOCYANATO-2,2'-STILBENEDISULFONATE 4,4'-DIISOTHIOCYANOSTILBENE-2,2'-SUFONIC ACID SODIUM SALT 4,4'-diisothiocyanato-2,2'-stilbenedisulfonic acid sodium 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC A. NA2-SLT HY DisodiuM 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonate  4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID DISODIUM SALT Disodium 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonate Hydrate 4,4'-DIISOTHIOCYANO-2,2'-STILBENEDISULFONIC ACID, DISODIUM SALT 4,4'-DIISOTHIOCYANATO-2,2'-STILBENEDISULFONIC ACID DISODIUM SALT 4,4'-DIISOTHIOCYANATO-STILBENE-2,2'-DISULFONIC ACID DISODIUM SALT 4,4'-DIISOTHIOCYANATO-2,2'-STILBENZENEDISULFONIC ACID DISODIUM SALT 4,4'-Diisocyano-2,2'- Disulfonic Acid Disodium Salt ,Crydtalline DIDS [4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid, disodiuM salt] 4,4''-DIISOTHIOCYANOSTILBENE-2,2''-DISULFONIC ACID, DISODIUM SALT, CRYSTALLINE Disodium 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonate Hydrate [Protein Modification Reagent] 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic Acid Disodium Salt [Protein Modification Reagent] | [Molecular Formula]
C16H8N2Na2O6S4 | [MDL Number]
MFCD00009638 | [MOL File]
67483-13-0.mol | [Molecular Weight]
498.48 |
Chemical Properties | Back Directory | [Appearance]
yellow to yellow-green or brown powder | [Melting point ]
>300°C | [density ]
1.54 | [storage temp. ]
2-8°C
| [solubility ]
0.1 M potassium bicarbonate: 50 mg/mL
| [form ]
powder
| [color ]
yellow
| [Stability:]
Recommend Desiccate and Storage at -20°C | [CAS DataBase Reference]
67483-13-0 |
Hazard Information | Back Directory | [Chemical Properties]
yellow to yellow-green or brown powder | [Uses]
ATP transport inhibitor, anion transport inhibitor, antiulcer | [Uses]
complexing agent for potassium ions | [Uses]
Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprotein on T helper lymphocytes and macrophages, blocking HIV type-1 growth at multiple stages of the viral life cycle.
Fluorescence: max. Abs. l = 341, max. Em. l = 415 (in water) | [Uses]
DIDS is a stilbene sulfonate that inhibits anionic transport. It has been used to inhibit Cl- uptake through plasma membrane-localized Cl- channels in order to study chloride transport. It also effectively inhibits various sodium-coupled bicarbonate transporters. | [storage]
Store at +4°C |
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