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ChemicalBook--->CAS DataBase List--->6708-06-1

6708-06-1

6708-06-1 Structure

6708-06-1 Structure
IdentificationBack Directory
[Name]

(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione
[CAS]

6708-06-1
[Synonyms]

Cyclo(Pro-Pro-)
L-Proline Anhydride
Cyclo(L-Pro-L-Pro-)
Vildagliptin Impurity 60
Vildagliptin Impurity 23
Vildagliptin impurities12
Vildagliptin Dipyrrolidine Impurity
1,7-diazatricyclo[7.3.0.03,7]dodecane-2,8-dione
Octahydro-5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione, octahydro-
(5aS,10aS)-Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
(5aS,10aS)-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aH)-dione
1,2,3,5aβ,6,7,8,10aβ-Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione
(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione
Vildagliptin Impurity 17/Vildagliptin Dipyrrolidine Impurity/octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
[Molecular Formula]

C10H14N2O2
[MOL File]

6708-06-1.mol
[Molecular Weight]

194.23
Chemical PropertiesBack Directory
[Melting point ]

146-148 °C
[Boiling point ]

413.5±25.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[pka]

-0.85±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

L-Proline Anhydride is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.
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