Identification | Back Directory | [Name]
VAR10300 dihydrochloride | [CAS]
64821-19-8 | [Synonyms]
M30 dihydrochloride M-30 dihydrochloride VAR10300 dihydrochloride MAO-IN-M30 dihydrochloride 5-[[Methyl(2-propyn-1-yl)amino]methyl]-8-quinolinol Dihydrochloride 5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride N-(8-Hydroxy-5-quinolylmethyl)-N-methyl-2-propynylamine dihydrochloride | [Molecular Formula]
C14H16Cl2N2O | [MDL Number]
MFCD20488063 | [MOL File]
64821-19-8.mol | [Molecular Weight]
299.196 |
Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO, heptane and xylene: ≥21mg/mL | [form ]
powder | [color ]
green-yellow | [Water Solubility ]
Soluble to 100 mM in water |
Hazard Information | Back Directory | [Uses]
M 30 Dihydrochloride is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA (Cat. No. 2547) induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson''s disease model. | [storage]
Store at -20°C |
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