Identification | Back Directory | [Name]
1,9-DIDEOXYFORSKOLIN | [CAS]
64657-18-7 | [Synonyms]
ddFSK Dideoxyforskolin 9-Dideoxyforskolin 1,9-DIDEOXYFORSKOLIN FORSKOLIN, 1,9-DIDEOXY DIDEOXYFORSKOLIN, 1,9- Dideoxyforskolin from Coleus forskohlii FORSKOLIN, 1,9-DIDEOXY-, COLEUS FORSKOHLII 1,9-DIDEOXYFORSKOLIN FROM COLEUSFORSKOHL II FORSKOLIN, 1,9-DIDEOXY ISOLATED FROM COL EUS 7β-acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one 7BETA-ACETOXY-8,13-EPOXY-6BETA-HYDROXY-LABD-14-EN-11-ONE 7BETA-ACETOXY-6BETA-HYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem (3R,6aα,10bβ)-3,4aβ,7,7,10aβ-Pentamethyl-3α-vinyl-5β-acetoxy-6β-hydroxydodecahydro-1H-naphtho[2,1-b]pyran-1-one (3R,6aα,10bβ)-5β-Acetoxy-3α-ethenyldodecahydro-6β-hydroxy-3,4aβ,7,7,10aβ-pentamethyl-1H-naphtho[2,1-b]pyran-1-one (3R,4aS,5S,6S,6aS,10aS,10bR)-6-hydroxy-3,4a,7,7,10a-pentaMethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chroMen-5-yl acetate (3R,4aS,5S,6S,6aS,10aS,10bR)-5-(Acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one 1H-Naphtho(2,1-B)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4A,7,7,10A-pentamethyl-, (3R,4as,5S,6S,6as,10as,10br)- 1H-Naphtho(2,1-B)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6-hydroxy-3,4A,7,7,10A-pentamethyl-, (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10abeta,10balpha))- | [Molecular Formula]
C22H34O5 | [MDL Number]
MFCD28125819 | [MOL File]
64657-18-7.mol | [Molecular Weight]
378.5 |
Chemical Properties | Back Directory | [Melting point ]
149-150℃ | [storage temp. ]
−20°C | [solubility ]
methanol: 28 mg/mL | [form ]
solid | [color ]
white | [optical activity]
[α]26/D +93.6°, c = 6.12 in chloroform(lit.) | [InChIKey]
ZKZMDXUDDJYAIB-OJPJTMFRSA-N |
Hazard Information | Back Directory | [Description]
Forskolin is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate, adenylyl cyclase. | [Uses]
1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP. | [Definition]
ChEBI: A labdane diterpenoid that is the 1,9-dideoxy derivative of forskolin. |
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