| Identification | Back Directory | [Name]
18BETA(H)-OLEAN-12-EN-3-ONE | [CAS]
638-97-1 | [Synonyms]
β-Amyron
β-Amyrone
Β-AMYRONE
β-Amyrone
beta-Amyrone
beta-AMyrenone
Olean-12-en-3-one
18(H)-Olean-12-en-3-one
18BETA(H)-OLEAN-12-EN-3-ONE
(6aR,6bS,8aR,12aS,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-2,4a,5,6,7,8,9,10,12,12a,14,14a-dodecahydro-1H-picen-3-one | [Molecular Formula]
C30H48O | [MDL Number]
MFCD04972118 | [MOL File]
638-97-1.mol | [Molecular Weight]
424.7 |
| Chemical Properties | Back Directory | [Melting point ]
177-178 °C | [Boiling point ]
488.3±45.0 °C(Predicted) | [density ]
1.01±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
β-Amyron is used as inhibitor of cyclooxygenase and lipoxygenase enzymes to study the structure-activity relationships of pentacyclic triterpenoids. | [in vivo]
β-Amyrone (local administration on ear, 0.1-0.6 mg/kg, a single dose) inhibits ear edema formation in phenol-induced edema mice[1]. | Animal Model: | Ear phenol-induced edema in Balb C mice[1] | | Dosage: | 0.1, 0.3, 0.6 mg/kg, a single dose | | Administration: | Local administration (20 ??L solution) on ear | | Result: | Inhibited ear edema formation in a dose-related manner (47% inhibition at the dose of 0.6mg/kg). |
| [IC 50]
COX-2 | [storage]
4°C, protect from light |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|