| Identification | Back Directory | [Name]
6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic acid | [CAS]
6314-14-3 | [Synonyms]
6-HYDROXY-2-(METHYLTHIO)-4-PYRIMIDINECARBOXYLIC ACID
6-Hydroxy-2-(methylthio)pyrimidine-4-carboxylic acid
6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic acid
2-(methylthio)-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid
2-(Methylthio)-6-oxo-3,6-dihydropyrimidine-4-carboxylic acid
4-Pyrimidinecarboxylic acid, 1,6-dihydro-2-(methylthio)-6-oxo-
2-(methylsulfanyl)-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid | [Molecular Formula]
C6H6N2O3S | [MDL Number]
MFCD00023236 | [MOL File]
6314-14-3.mol | [Molecular Weight]
186.19 |
| Hazard Information | Back Directory | [Uses]
6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic Acid has shown binding to HCR-13pf of MMP-13 hemopexin domain with no crossreactivity to MMP-1 and 8 which could serve as building block for development of drug for osteoarthritis (OA) and rheumatoid arthritis (RA). It can be useful in the structure-??activity relationship studies of pyrimidine base analogs as ligands of orotate phosphoribosyltransferase as well as allosteric inhibitors of a mammalian lectin. |
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