| Identification | Back Directory | [Name]
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine | [CAS]
623950-02-7 | [Synonyms]
EOS-61912
Eluxadoline int1
Eluxadoline Intermediate 2
L-Phenylalanine propionic acid
4-(aminocarbonyl)-N-[(1,1-dimethylethoxy)
4'-Carbamoyl N-Boc-2',6'-dimethyl-L-Phenylalanine
4-(Aminocarbonyl)-N-Boc-2,6-dimethyl-L-phenylalanine
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimet...
(S)-2-(Boc-Amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic Acid
(S)-2-(N-BOC-amino)-3-(4-formamido-2,6-dimethylphenyl)propanoic acid
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
(S)-2-(tert-butoxycarbonylaMino)-3-(4-carbaMoyl-2,6-diMethylphenyl)propanoic aci
L-Phenylalanine, 4-(aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-
(s)-2-(tert-butoxycarbonylaMino)-3-(4-carbaMoyl-2,6-diMethylphenyl)propanoic acid
(S)-2-tert-Butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionic acid
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine###NA
(2S)-2{[(tert-butoxy)carbonyl]amino}-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid
Eluxadoline: 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
(S,E)-2-((tert-butoxy(hydroxy)methylene)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid
(2S)-3-(4-carbamoyl-2,6-dimethylphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid | [EINECS(EC#)]
633-600-1 | [Molecular Formula]
C17H24N2O5 | [MDL Number]
MFCD20528368 | [MOL File]
623950-02-7.mol | [Molecular Weight]
336.38 |
| Chemical Properties | Back Directory | [Melting point ]
>210℃ | [Boiling point ]
497.1±45.0 °C(Predicted) | [density ]
1.201 | [storage temp. ]
Sealed in dry,2-8°C | [form ]
Solid | [pka]
3.88±0.17(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C17H24N2O5/c1-9-6-11(14(18)20)7-10(2)12(9)8-13(15(21)22)19-16(23)24-17(3,4)5/h6-7,13H,8H2,1-5H3,(H2,18,20)(H,19,23)(H,21,22)/t13-/m0/s1 | [InChIKey]
ZLUHLTMMROGKKD-ZDUSSCGKSA-N | [SMILES]
C(O)(=O)[C@H](CC1=C(C)C=C(C(N)=O)C=C1C)NC(OC(C)(C)C)=O | [CAS DataBase Reference]
623950-02-7 |
| Hazard Information | Back Directory | [Description]
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine is a phenylalanine derivative. It is mainly used as a pharmaceutical intermediate component in the preparation of opioid modulators and eluxadoline. | [Uses]
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine is an intermediate used to prepare potential Dual delta-opioid antagonist/μ-opioid agonist used in the treatment of diarrhea. Irritable bowel syndrome. |
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