| Identification | Back Directory | [Name]
Fibrinopeptide A, human (TFA) | [CAS]
61533-47-9 | [Synonyms]
Human fibrinopeptide A TFA
Fibrinopeptide A, human (TFA) | [Molecular Formula]
C65H98F3N19O28 | [MDL Number]
MFCD18632600 | [MOL File]
61533-47-9.mol | [Molecular Weight]
1650.6 |
| Hazard Information | Back Directory | [Uses]
Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain[1]. | [in vivo]
Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2]. | [References]
[1] Riedel T, et al. Fibrinopeptides A and B release in the process of surface fibrin formation. Blood. 2011 Feb 3;117(5):1700-6. DOI:10.1182/blood-2010-08-300301
[2] Manolis AS, et al. Plasma level changes of fibrinopeptide A after uncomplicated coronary angioplasty. Clin Cardiol. 1993 Jul;16(7):548-52. DOI:10.1002/clc.4960160707 |
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