| Identification | Back Directory | [Name]
3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, diammonium salt (9CI) | [CAS]
609343-82-0 | [Synonyms]
3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide, diammonium salt (9CI) | [Molecular Formula]
C20H27N11O14P2 | [MOL File]
609343-82-0.mol | [Molecular Weight]
707.45 |
| Hazard Information | Back Directory | [Biological Activity]
Cyclic di-GMP (c-di-GMP) diammonium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species[1][2]. | [storage]
Store at -20°C | [References]
[1]. Wang Z, et al. STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice. Cancer Immunol Immunother. 2015;64(8):1057-1066. [2]. Burdette DL, et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8. |
|
|