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ChemicalBook--->CAS DataBase List--->60388-53-6

60388-53-6

60388-53-6 Structure

60388-53-6 Structure
IdentificationBack Directory
[Name]

(+/-)AMETHOPTERIN
[CAS]

60388-53-6
[Synonyms]

dl-MTX
6-mtx(dl)
AKOS 93273
NSC 117356
dl-amethopterin
dl-methotrexate
(+/-)AMETHOPTERIN
dl-Methylaminopterin
(plus-minus)-amethopterin
DL-Amethopterin hydrate,95%
(plus-Minus)-aMethopterin(-20`C)
DL-4-Amino-N10-methylpteroylglutamic acid
DL-Methotrexate DipotassiuM Salt Dihydrate
n-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-dl-glutamicacid
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-DL-glutamic acid
DL-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI)
(±)Amethopterin hydrate,4-Amino-10-methylfolic acid, DL-4-Amino-N10-methylpteroylglutamic acid, MTX, Methylaminopterin
[EINECS(EC#)]

262-213-7
[Molecular Formula]

C20H22N8O5
[MDL Number]

MFCD00064369
[MOL File]

60388-53-6.mol
[Molecular Weight]

454.44
Chemical PropertiesBack Directory
[Appearance]

yellow to orange crystalline powder
[Melting point ]

195 °C (dec.)(lit.)
[density ]

1.536±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

H2O: Add a minimal amount of 0.1燦 NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1爓eek refrigerated and for 1爉onth frozen at?#8722;20?#x00b0;C.insoluble
[form ]

powder
[pka]

3.47±0.10(Predicted)
[color ]

yellow
Hazard InformationBack Directory
[Chemical Properties]

yellow to orange crystalline powder
[Uses]

antineoplastic, antirheumatic, folic acid antagonist
[Uses]

Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
[Definition]

ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

61-25-36/38-23/24/25
[Safety Statements ]

53-26-36/37-45-36/37/39
[RIDADR ]

UN 1544 6.1/PG 2
[WGK Germany ]

3
[RTECS ]

MA1224100
Spectrum DetailBack Directory
[Spectrum Detail]

(+/-)AMETHOPTERIN(60388-53-6)MS
(+/-)AMETHOPTERIN(60388-53-6)13CNMR
(+/-)AMETHOPTERIN(60388-53-6)IR1
(+/-)AMETHOPTERIN(60388-53-6)IR2
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