Identification | Back Directory | [Name]
Calcium folinatc | [CAS]
6035-45-6 | [Synonyms]
Folaren Foliben Folidan NSC-3590 Calcium folinatc Folinic acid calcium salt Leucovorin calcium pentahydrate FOLINIC ACID(SEE CALCIUM FOLINATE) CALCIUM FOLINATE(FOLINIC ACID)(RG) FOLINIC ACID CALCIUM CELL CULTURE TESTED Folinic acid, calcium salt pentahydrate,95-105% % Folinic acid, calcium salt pentahydrate, 95.0-105.0% CalciuM folinate, pentahydrate / 5-ForMyl-5,6,7,8-tetrahydrofolic acid, calciuM salt / Leucovorin Calcium (2S)-2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate N-[4-[[(2-AMino-5-forMyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid CalciuM Salt Pentahydrate N-[4-[[(2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, calcium salt, hydrate (1:1:5) | [Molecular Formula]
C20H21CaN7O7 | [MDL Number]
MFCD00006704 | [MOL File]
6035-45-6.mol | [Molecular Weight]
511.5 |
Chemical Properties | Back Directory | [Appearance]
yellowish-white to yellow powder | [Melting point ]
240-250°C | [alpha ]
D21 +14.9° (c = 1 in water) | [storage temp. ]
Store at RT. | [solubility ]
insoluble in DMSO; insoluble in EtOH; ≥15.04 mg/mL in H2O with gentle warming | [form ]
powder
| [color ]
Yellow-white to yellow |
Hazard Information | Back Directory | [Chemical Properties]
yellowish-white to yellow powder | [Uses]
An intermediate product of the metabolism of Folic Acid. This compound is a mixture of diastereomers. | [Uses]
Antianemic | [Brand name]
Wellcovorin (GlaxoSmithKline). | [Biological Activity]
human lymphoid cell lines were studied for leucovorin requirements to protect from methotrexate (mtx)-induced growth suppression. over a 72h continuous exposure leucovorin provided better protection to the cell lines laz-007 and raji than to the cell line |
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