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ChemicalBook--->CAS DataBase List--->603272-51-1

603272-51-1

603272-51-1 Structure

603272-51-1 Structure
IdentificationBack Directory
[Name]

GSK-3 inhibitor 1
[CAS]

603272-51-1
[Synonyms]

GSK-3 inhibitor 1
PubChem ID: 78357782
3-(9-Fluoro-1,2,3,4-tetrahydropyrrolo[3,2,1-jk][1,4]benzodiazepin-7-yl)-4-imidazo[1,2-a]pyridin-3-yl-1H-pyrrole-2,5-dione monohydrochloride
[Molecular Formula]

C22H17ClFN5O2
[MOL File]

603272-51-1.mol
[Molecular Weight]

437.854
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Powder
[color ]

Yellow to orange
Hazard InformationBack Directory
[Uses]

GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny)[1][2].
[IC 50]

GSK-3
[storage]

Store at -20°C
[References]

[1] SOLUBILIZED COMPOSITIONS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING GSK3 INHIBITORS: III. 20170252449 A1
[2] Christopher Loose, et al. 1h-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells. Patent WO2018125746A1.
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