| Identification | Back Directory | [Name]
DIHYDROCYCLOSPORIN A | [CAS]
59865-15-5 | [Synonyms]
CS-2523
59865-15-5
Capecitabine Imp.G
Dihydrocyclosporin
DIHYDROCYCLOSPORIN A
Dihydrocyclosporine A
Cyclosporin Impurity 10
Cyclosporine Impurity 10
Cyclosporin A Dihydro IMpurity
Dihydrocyclosporin A reference
Cyclosporin Impurity 10（Dihydrocyclosporin A）
6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A
Cyclosporin A,6-[(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)octanoic acid]-
Dihydrocyclosporine A/6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A
(3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)
(3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-] | [Molecular Formula]
C62H113N11O12 | [MDL Number]
MFCD08458303 | [MOL File]
59865-15-5.mol | [Molecular Weight]
1204.63 |
| Chemical Properties | Back Directory | [Melting point ]
120-125?C | [Boiling point ]
1285.3±65.0 °C(Predicted) | [density ]
1.012±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.33±0.70(Predicted) | [color ]
White | [InChIKey]
TYFOVYYNQGNDKH-AAJDKDKZNA-N |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A Cyclosporin A (C988900) analog, an immunosuppressant. | [Uses]
Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections. | [Side effects]
Dihydrocyclosporine A has no obvious nephrotoxic effect, but it exhibits hepatotoxic effects, often leading to hypertension. |
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