| Identification | Back Directory | [Name]
kakkalide | [CAS]
58274-56-9 | [Synonyms]
kakkalide
kakkalide USP/EP/BP
Kakkalide,Inhibitor,inhibit
4H-1-Benzopyran-4-one, 5-hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]-
5-Hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-[(6-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl)oxy]-4H-1-benzopyran-4-one
5-Hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one | [Molecular Formula]
C28H32O15 | [MDL Number]
MFCD09970384 | [MOL File]
58274-56-9.mol | [Molecular Weight]
608.546 |
| Chemical Properties | Back Directory | [Melting point ]
250-252 °C | [Boiling point ]
902.0±65.0 °C(Predicted) | [density ]
1?+-.0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
6.08±0.20(Predicted) | [color ]
White to off-white | [LogP]
-0.292 (est) |
| Hazard Information | Back Directory | [Uses]
Kakkalide is an isoflavone derived from the flowers of Pueraria lobata. Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species (ROS)-associated inflammation[1]. | [References]
[1] Zhang D, et al. Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species-associated inflammation. J Diabetes. 2013 Mar;5(1):13-24. DOI:10.1111/1753-0407.12017 |
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