| Identification | Back Directory | [Name]
20-HYDROXY PROSTAGLANDIN F2ALPHA | [CAS]
57930-92-4 | [Synonyms]
XQXUYZDBZCLAQO-UNKHNRNISA-N
20-hydroxy Prostaglandin F2α
20-HYDROXY PROSTAGLANDIN F2ALPHA
20-hydroxy Prostaglandin F2α Lipid Maps MS Standard
9ALPHA,11ALPHA,15S,20-TETRAHYDROXY-PROSTA-5Z,13-E-DIEN-1-OIC ACID
9alpha,11alpha,15S,20-Teterahydroxy-prosta-5Z,13-E-dien-1-oic acid
Prosta-5,13-dien-1-oic acid, 9,11,15,20-tetrahydroxy-, (5Z,9α,11α,13E,15S)- | [Molecular Formula]
C20H34O6 | [MDL Number]
MFCD00216075 | [MOL File]
57930-92-4.mol | [Molecular Weight]
370.48 |
| Chemical Properties | Back Directory | [solubility ]
10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a) |
| Hazard Information | Back Directory | [Description]
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.1 | [Uses]
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway. | [Definition]
ChEBI: 20-Hydroxy-PGF2alpha is a prostanoid. | [References]
1. Devereux, T.R., Fouts, J.R., and Eling, T.E. Metabolism of prostaglandin PG-F2α by freshly isolated alveolar type II cells from lungs of adult male or pregnant rabbits Prostaglandins Leukot. Med. 27,43-52(1987). |
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