| Identification | Back Directory | [Name]
Furo[2',3',4':3,4]indeno[1,2-b:6,7-b']bis[1]benzopyran-5b,7(5H)-dicarboxylic acid, 7,7a,7b,8,14,14b-hexahydro-4,7,13-trihydroxy-2,11-dimethyl-5,14-dioxo-, dimethyl ester, (5bS,7S,7aR,7bR,14bS)- | [CAS]
571194-06-4 | [Synonyms]
Remisporine B
Furo[2',3',4':3,4]indeno[1,2-b:6,7-b']bis[1]benzopyran-5b,7(5H)-dicarboxylic acid, 7,7a,7b,8,14,14b-hexahydro-4,7,13-trihydroxy-2,11-dimethyl-5,14-dioxo-, dimethyl ester, (5bS,7S,7aR,7bR,14bS)- | [Molecular Formula]
C30H24O12 | [MDL Number]
MFCD33021346 | [MOL File]
571194-06-4.mol | [Molecular Weight]
576.51 |
| Hazard Information | Back Directory | [Biological Activity]
Remisporine B is a polyketide and derivative of remisporine A that has been found in Penicillium and has immunosuppressant activity.1,2 It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 30.1 and 32.4 μg/ml, respectively).1 | [storage]
-20°C | [References]
1.Liu, H., Chen, S., Liu, W., et al.Polyketides with immunosuppressive activities from mangrove endophytic fungus Penicillium sp. ZJ-SY2Mar. Drugs14(12)217(2016)
2.Kong, F., and Carter, G.T.Remisporine B, a novel dimeric chromenone derived from spontaneous Diels-Alder reaction of remisporine ATetrahedron Lett.44(15)3119-3122(2003)
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