| Identification | Back Directory | [Name]
PSEUDOISOCYTIDINE | [CAS]
57100-18-2 | [Synonyms]
PSEUDOISOCYTIDINE
PSEUDOISOCYTIDINE HYDROCHLORIDE
2-Amino-5-β-D-ribofuranosylpyrimidin-4(1H)-one
2-Amino-5-β-D-ribofuranosylpyrimidine-4(3H)-one
4(1H)-Pyrimidinone,2-amino-5-b-D-ribofuranosyl-
4(1H)-Pyrimidinone, 2-amino-5-β-D-ribofuranosyl-
2-AMino-5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-4(1H)-one | [Molecular Formula]
C9H13N3O5 | [MDL Number]
MFCD04117882 | [MOL File]
57100-18-2.mol | [Molecular Weight]
243.22 |
| Hazard Information | Back Directory | [Uses]
Pseudoisocytidine is an analog of the nucleoside Cytidine . It has been shown to inhibit DNA methylation by inactivation of DNA methyltransferase and induce the expression of the human hypoxanthine-??guanine phosphoribosyltransferase (HPRT). It can be useful in the study of nucleoside recognition by cytidine deaminase, which is responsible for the degradation and inactivation of several cytidine-??based antitumor drugs such as cytarabine , gemcitabine , decitabine , and azacytidine . |
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