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ChemicalBook--->CAS DataBase List--->570407-10-2

570407-10-2

570407-10-2 Structure

570407-10-2 Structure
IdentificationBack Directory
[Name]

2-ThiazolaMine, 4-(4-chloro-2-thienyl)-
[CAS]

570407-10-2
[Synonyms]

Avatrombopag Impurity 8
4-(4-Chloro-2-thienyl)-2-thiazolamine
2-ThiazolaMine, 4-(4-chloro-2-thienyl)-
4-(4-Chlorothiophen-2-yl)thiazol-2-amine
2-Amino-4-(4-chlorothiophen-2-yl)thiazole
4-(4-chlorothiophen-2-yl)-1,3-thiazol-2-amine
2-ThiazolaMine, 4-(4-chloro-2-thienyl)- 2-ThiazolaMine
2-ThiazolaMine, 4-(4-chloro-2-thienyl)- 2-ThiazolaMine, 4-(4-chloro-2-thienyl)-
[EINECS(EC#)]

1312995-182-4
[Molecular Formula]

C7H5ClN2S2
[MDL Number]

MFCD24627156
[MOL File]

570407-10-2.mol
[Molecular Weight]

216.711
Chemical PropertiesBack Directory
[Boiling point ]

395.3±27.0 °C(Predicted)
[density ]

1.535±0.06 g/cm3(Predicted)
[pka]

3.47±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard InformationBack Directory
[Uses]

4-(4-Chloro-2-thienyl)-2-thiazolamine can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
[Synthesis]

Synthesis_570407-10-2
Bromine was added to an ether solution of 4-chloro-2-acetylthiophene under ice cooling, and the mixture was stirred at room temperature for 2 hours to obtain a brominated compound. Thiourea was added to an EtOH solution of the brominated compound at room temperature, and the mixture was stirred overnight at 80??C to obtain 2-amino-4-(4-chlorothiophen-2-yl)thiazole.
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