| Identification | Back Directory | [Name]
1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE | [CAS]
56952-01-3 | [Synonyms]
18:0 PC D70
1,2-Distearoyl-d35-sn-glycero-3-PC
1,2-DISTEAROYL-D70-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE
1,2-DISTEAROYL-D70-SN-GLYCERO-3-PHOSPHOCHOLINE;18:0 PC-D70 | [Molecular Formula]
C44H88NO8P | [MDL Number]
MFCD00674391 | [MOL File]
56952-01-3.mol | [Molecular Weight]
790.16 |
| Hazard Information | Back Directory | [Description]
1,2-Distearoyl-d70-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-distearoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Distearoyl-sn-glycero-3-PC is a phospholipid containing the saturated long-chain (18:0) fatty acid stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.1,2 | [Uses]
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2]. | [References]
1. H?yrup, P., Mouritsen, O.G., and J?rgensen, K. Phospholipase A2 activity towards vesicles of DPPC and DMPC-DSPC containing small amounts of SMPC Biochim. Biophys. Acta 1515(2),133-143(2001).
2. Heberle, F.A., and Feigenson, G.W. Phase separation in lipid membranes Cold Spring Harb. Perspect. Biol. 3(4),1-13(2011). |
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