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ChemicalBook--->CAS DataBase List--->56701-24-7

56701-24-7

56701-24-7 Structure

56701-24-7 Structure
IdentificationBack Directory
[Name]

2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
[CAS]

56701-24-7
[Synonyms]

VESTITOL
(+/-)-Vestitol
VESTITOL(RG)(PLEASE CALL)
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
3-(2-Hydroxy-4-methoxyphenyl)-7-chromanol
3-(2-Hydroxy-4-methoxyphenyl)chroman-7-ol
3-(2-Hydroxy-4-Methoxyphenyl)-3,4-Dihydro-2H-Chromen-7-Ol
3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol
3-(2-Hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(2-hydroxy-4-methoxyphenyl)-
[Molecular Formula]

C16H16O4
[MDL Number]

MFCD00075893
[MOL File]

56701-24-7.mol
[Molecular Weight]

272.3
Chemical PropertiesBack Directory
[Melting point ]

172-179℃
[Boiling point ]

418.5±45.0 °C(Predicted)
[density ]

1.282±0.06 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,Store in freezer, under -20°C
[solubility ]

DMSO: 2mg/mL, clear
[form ]

powder
[pka]

9.53±0.40(Predicted)
[color ]

white to beige
Hazard InformationBack Directory
[Definition]

ChEBI: Vestitol is a member of the class of hydroxyisoflavans that is isoflavan substituted by hydroxy groups at positions 7 and 2' and a methoxy group at position 4'. Isolated from Glycyrrhiza uralensis, it exhibits anti-inflammatory activity. It has a role as an anti-inflammatory agent, a plant metabolite and a phytoalexin. It is an aromatic ether, a member of hydroxyisoflavans and a methoxyisoflavan.
[Biological Activity]

Hydroxyisoflavan isolated from Cuban and Brazilian red propolis th at exhibits potent anti-inflammatoryanti-viraland antiparasitic activities.

(±)-Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolislicorice root and other sources th at exhibits potent anti-inflammatoryanti-viraland antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 μg/ml).
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