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ChemicalBook--->CAS DataBase List--->55721-11-4

55721-11-4

55721-11-4 Structure

55721-11-4 Structure
IdentificationBack Directory
[Name]

Secalciferol
[CAS]

55721-11-4
[Synonyms]

k-dr
osteod
ro21-5816
Stilbitol
Secalciferol
(24r)-hydroxycalcidiol
kinase insert domain receptor
(24R)-24,25-Dihydroxyvitamin D3
Human KDR/VEGFR2 Protein, Fc Tag
Human KDR/VEGFR2 Protein, His Tag
24(r),25-dihydroxycholecalciferol
(24R)-24,25-Dihydroxycholecalciferol
24R,25-Dihydroxyvitamin D3 (Solution)
ANTI-VGFR2 antibody produced in rabbit
protein-tyrosine kinase receptor Flk-1
Human KDR/VEGFR2 Protein, His & GST Tag
Recombinant Human CD309/KDR Protein, His Tag
vascular endothelial growth factor receptor 2
Secalciferol/ 24R, 25-Dihydroxycholecalciferol
Anti-VEGFR2, C-Terminal antibody produced in rabbit
Recombinant Human CD309/VEGFR2/KDR Protein, His tag
ANTI-VEGFR2 (FLK1/KDR)(C-TERMINAL) antibody produced in rabbit
7,10(19)-triene-3,24,25-triol,(3-beta,5z,7e,24r)-10-secocholesta-5
(3-beta,5z,7e,24r)-9,10-secocholesta-5,7,10(19)-triene-3,24,25-triol
Secalciferol, 24R,25-dihydroxycholecalciferol, 24R,25-dihydroxyvitamin D3, 24R 25 DHCC
2,3-Heptanediol, 2-methyl-6-[(1R,3aS,4E,7aR)-octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-7a-methyl-1H-inden-1-yl]-, (3R,6R)-
(3R,6R)-6-[(1R,3aR,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidene-cyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methyl-heptane-2,3-diol
[Molecular Formula]

C27H44O3
[MDL Number]

MFCD00941417
[MOL File]

55721-11-4.mol
[Molecular Weight]

416.64
Chemical PropertiesBack Directory
[Melting point ]

63-65°C
[Boiling point ]

474.91°C (rough estimate)
[density ]

1.0362 (rough estimate)
[refractive index ]

1.4700 (estimate)
[storage temp. ]

Amber Vial, -20°C Freezer, Under Inert Atmosphere
[solubility ]

Soluble in DMSO
[form ]

Powder
[pka]

14.67±0.29(Predicted)
[color ]

White to off-white
[biological source]

synthetic
[BRN ]

4567039
[Stability:]

Light Sensitive, Temperature Sensitive
[InChIKey]

FCKJYANJHNLEEP-AOWQBJNISA-N
Safety DataBack Directory
[Hazard Codes ]

T+
[Risk Statements ]

28
[Safety Statements ]

28-36/37-45
[RIDADR ]

2811
[WGK Germany ]

3
[RTECS ]

VS2895000
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

A labelled metabolite of Vitamin D, a possible anti-inflammatory steroid.
[Uses]

A labelled metabolite of Vitamin D, a possibly anti-inflammatory steroid.
[Uses]

A metabolite of Vitamin D, a possibly anti-inflammatory steroid.
[Definition]

ChEBI:(24R)-24,25-dihydroxycalciol is a seco-cholestane, a hydroxy seco-steroid and a hydroxycalciol. It has a role as a human metabolite.
[Brand name]

Osteo D (Teva, Israel).
[Biological Activity]

(24R)-24,25-Dihydroxyvitamin D3 plays an essential role in calcium and phosphorus homeostasis. (24R)-24,25-Dihydroxyvitamin D3 along with 1α,25(OH)2D3 stimulates bone metabolism.''Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol) is a synthetic analog th at is metabolized to 1,25-dihydroxycholecalciferolthe biologically active form of vitamin D3. Other analogues of cholecalciferol result from different hydroxylations. 24R,25-Dihydroxyvitamin D3 is a catabolite of 25-Dihydroxyvitamin D3 and a putative regulator of developmental bone formation. 24R,25-Dihydroxyvitamin D3 is a substrate for renal 25-hydroxyvitamin D3 1 α-hydroxylase. 24R,25-Dihydroxyvitamin D3 is an endogenous regulator of apo A-I synthesis through a VDR-independent signaling mechanism a
[storage]

4°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
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