Identification | Back Directory | [Name]
NEUROTENSIN | [CAS]
55508-42-4 | [Synonyms]
C01836 NEUROTENSIN Neurotensin【ox】 Neurotensin【rat】 PYR-LYENKPRRPYIL NEUROTENSIN (1-13) NEUROTENSIN, BOVINE Neurotensin(cattle) NEUROTENSIN USP/EP/BP Neurotensin, ≥95%(HPLC) NEUROTENSIN (HUMAN, BOVINE, CANINE) NEUROTENSIN (HUMAN, BOVINE, CANINE) 2ACOH 6H2O GLP-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU PGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU-OH PYROGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH pyroGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH PYROGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TRP-ILE-LEU OH PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU 2ACOH 6H2O 5-Oxo-L-Pro-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg-L-Arg-L-Pro-L-Tyr-L-Ile-L-Leu-OH L-Leucine, 5-oxo-L-prolyl-L-leucyl-L-tyrosyl-L-α-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl- | [Molecular Formula]
C78H121N21O20 | [MDL Number]
MFCD00076678 | [MOL File]
55508-42-4.mol | [Molecular Weight]
1672.95 |
Hazard Information | Back Directory | [Definition]
ChEBI: Neurotensin is a 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. It has a role as a human metabolite, a mitogen, a neurotransmitter and a vulnerary. It is a conjugate base of a neurotensin(1+). | [General Description]
Neurotensin is a 13-amino-acid peptide, first isolated frombovine hypothalamus. It has now been identified in the intestinaltract. The ileal mucosa contains 90% of the total neurotensinof the body. It is implicated as a releasing factor forseveral adenohypophyseal hormones. It causes vasodilatation,increases vascular permeability, and increases gastrinsecretion. It decreases secretion of gastric acid and secretin. |
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