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ChemicalBook--->CAS DataBase List--->55508-42-4

55508-42-4

55508-42-4 Structure

55508-42-4 Structure
IdentificationBack Directory
[Name]

NEUROTENSIN
[CAS]

55508-42-4
[Synonyms]

C01836
NEUROTENSIN
Neurotensin【ox】
Neurotensin【rat】
PYR-LYENKPRRPYIL
NEUROTENSIN (1-13)
NEUROTENSIN, BOVINE
Neurotensin(cattle)
NEUROTENSIN USP/EP/BP
Neurotensin, ≥95%(HPLC)
NEUROTENSIN (HUMAN, BOVINE, CANINE)
NEUROTENSIN (HUMAN, BOVINE, CANINE) 2ACOH 6H2O
GLP-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU
PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU
PGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU
PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU-OH
PYROGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU
pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
pyroGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
PYROGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TRP-ILE-LEU OH
PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU 2ACOH 6H2O
5-Oxo-L-Pro-L-Leu-L-Tyr-L-Glu-L-Asn-L-Lys-L-Pro-L-Arg-L-Arg-L-Pro-L-Tyr-L-Ile-L-Leu-OH
L-Leucine, 5-oxo-L-prolyl-L-leucyl-L-tyrosyl-L-α-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-
[Molecular Formula]

C78H121N21O20
[MDL Number]

MFCD00076678
[MOL File]

55508-42-4.mol
[Molecular Weight]

1672.95
Chemical PropertiesBack Directory
[density ]

1.46±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

3.41±0.10(Predicted)
Hazard InformationBack Directory
[Definition]

ChEBI: Neurotensin is a 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinson's disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. It has a role as a human metabolite, a mitogen, a neurotransmitter and a vulnerary. It is a conjugate base of a neurotensin(1+).
[General Description]

Neurotensin is a 13-amino-acid peptide, first isolated frombovine hypothalamus. It has now been identified in the intestinaltract. The ileal mucosa contains 90% of the total neurotensinof the body. It is implicated as a releasing factor forseveral adenohypophyseal hormones. It causes vasodilatation,increases vascular permeability, and increases gastrinsecretion. It decreases secretion of gastric acid and secretin.
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