Identification | Back Directory | [Name]
BETAMETHASONE BUTYRATE PROPIONATE | [CAS]
5534-02-1 | [Synonyms]
Salex Antebate Anflavate BETAMETHASONE BUTYRATE PROPIONATE Betamethasone 17-butyrate 21-propionate 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-butyrate 21-propionate Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16-methyl-17-(1-oxobutoxy)-21-(1-oxopropoxy)-,(11b,16b)- Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17-(1-oxobutoxy)-21-(1-oxopropoxy)-, (11β,16β)- [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate butyric acid [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-3-keto-10,13,16-trimethyl-17-(2-propionyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester | [Molecular Formula]
C29H39FO7 | [MDL Number]
MFCD00865998 | [MOL File]
5534-02-1.mol | [Molecular Weight]
518.61 |
Chemical Properties | Back Directory | [Melting point ]
approximate 152℃ | [Boiling point ]
613.0±55.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Dioxane (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [pka]
12.88±0.70(Predicted) | [color ]
White to Off-White |
Hazard Information | Back Directory | [Description]
Betamethasone butyrate propionate (BBP) was introduced in Japan as a
topical antiinflammatory agent. It is a synthetic corticosteroid with strong
antiinflammatory activity at the site of inflammation but without topical or systemic
side effects. On paper disk granuloma in rats, BBP was shown to have higher
degree of dissociation between antiinflammation efficacy and systemic side effects
than other agents in this class. Antipyretic/analgesic properties have also been
reported. | [Originator]
Mitsubishi Kasai (Japan) | [Uses]
Betamethasone-17-butyrate-21-propionate are used in the treatment of vitiligo vulgaris with the combination therapy of topical steroid and vitamin D3 compound. | [Definition]
ChEBI: Betamethasone butyrate propionate is a corticosteroid hormone. | [Brand name]
Antebate; Antevate |
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Energy Chemical
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