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ChemicalBook--->CAS DataBase List--->55077-30-0

55077-30-0

55077-30-0 Structure

55077-30-0 Structure
IdentificationBack Directory
[Name]

Aclatonium napadisilate
[CAS]

55077-30-0
[Synonyms]

Abovis
TM 723
Aclatonium
aclatonium napadisilate
aclatonium napadisylate
(2-Acetoxypropionyl)choline
Napadisilic acid aclatonium
Aclatonium napadisilate USP/EP/BP
2-(2-acetyloxy-1-oxopropoxy)ethyl-trimethylammonium
2-[2-(Acetyloxy)-1-oxopropyloxy]-N,N,N-trimethylethanaminium
(2-acetyllactoyloxyethyl)trimethylammonium 1,5-naphthalenedisulfonate
(2-acetyllactoyloxyethyl)trimethylammonium hemi-1,5-naphthalenedisulfonate
2-(2-acetyloxypropanoyloxy)ethyl-trimethylazanium,naphthalene-1,5-disulfonate
Ethanaminium, 2-[2-(acetyloxy)-1-oxopropoxy]-N,N,N-trimethyl-, 1,5-naphthalenedisulfonate (2:1)
1,5-Naphthalenedisulfonic acid, ion(2-), bis[2-[2-(acetyloxy)-1-oxopropoxy]-N,N,N-trimethylethanaminium] (9CI)
2-(2-acetyloxypropanoyloxy)ethyl-[2-[2-(2-acetyloxypropanoyloxy)ethyl-dimethyl-ammonio]ethyl]-dimethyl-azanium naphthalene-1,5-disulfonate
[EINECS(EC#)]

1592732-453-0
[Molecular Formula]

C30H44N2O14S2
[MOL File]

55077-30-0.mol
[Molecular Weight]

720.805
Chemical PropertiesBack Directory
[Melting point ]

189-191°
[color ]

Crystals
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Isopropyl acetate-->Choline hydroxide
Hazard InformationBack Directory
[Originator]

Abovis ,Toyama ,Japan ,1981
[Manufacturing Process]

5.2 g of bis(choline)-naphthalene-1,5-disulfonate was suspended in 30 ml of acetonitrile, and 10 g of lactic acid anhydride diacetate was added thereto. This mixture was refluxed for 3 hours. The resulting reaction mixture was allowed to stand at room temperature while cooling to precipitate the desired product crystals, which were collected by filtration. 5.5 g (76% yield) of the desired product having a melting point of 189°C to 191°C were obtained.
[Therapeutic Function]

Cholinergic
[Safety Profile]

Poison by intravenous route.Moderately toxic by subcutaneous route. An experimentalteratogen. Other experimental reproductive effects. Whenheated to decomposition it emits toxic fumes of NOx andSOx. A cholinergic agent.
Safety DataBack Directory
[Toxicity]

LD50 in mice: 15 g/kg orally, 826 mg/kg s.c. (Miura); in dogs: >10 g/kg orally (Takai)
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