| Identification | Back Directory | [Name]
4-CYANOPHENYLACETIC ACID | [CAS]
5462-71-5 | [Synonyms]
4-CYANOPHENYLACETIC ACID
4-Cyanobenzeneacetic acid
2-(4-CYANOPHENYL)ACETIC ACID
Benzeneacetic acid, 4-cyano-
4-Cyanophenylacetic acid 97%
4-Cyanophenylacetic acid ,98%
2-(4-cyanophenyl)ethanoic acid
4-Cyanophenylacetic Acid(WX610399) | [EINECS(EC#)]
226-753-7 | [Molecular Formula]
C9H7NO2 | [MDL Number]
MFCD06798066 | [MOL File]
5462-71-5.mol | [Molecular Weight]
161.16 |
| Chemical Properties | Back Directory | [Melting point ]
150-154 °C(lit.)
| [Boiling point ]
355.2±25.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Soluble in CHCl3, THF, dioxane. | [form ]
Powder | [pka]
3.93±0.10(Predicted) | [color ]
White to pale brown |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white crystals | [Uses]
4-Cyanophenylacetic acid can be used as a nitrile precursor to synthesize 1,2,4,5-tetrazines by reacting with aliphatic nitriles and hydrazine in the presence of Lewis acid metal catalysts.
It can also be used as a reactant to prepare:
- 4-pyrrolo[1,2-a]quinoxalin-4-ylbenzonitrile by copper-catalyzed reaction with 1-(2-aminoaryl)pyrrole in the presence of 2,2′-bipyridyl as the ligand.
- 4-(1,2-Diphenyl-1H-imidazol-4-yl)benzonitrile by one-pot three-component reaction with N-phenylbenzamidine and nitromethane via activation of C-H and N-H bonds.
- 4-Cyano-N,N-di-2-propen-1-ylbenzeneacetamide by reacting with diallylamine.
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