| Identification | Back Directory | [Name]
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester | [CAS]
54280-71-6 | [Synonyms]
Nemadipine-A
Nemadipine-A - CAS 54280-71-6 - Calbiochem
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-, 3,5-diethyl ester | [Molecular Formula]
C19H18F5NO4 | [MDL Number]
MFCD00335178 | [MOL File]
54280-71-6.mol | [Molecular Weight]
419.34 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
DMSO:20.0(Max Conc. mg/mL);47.69(Max Conc. mM)
Ethanol:15.0(Max Conc. mg/mL);35.77(Max Conc. mM)
Methanol:100.0(Max Conc. mg/mL);238.46(Max Conc. mM) | [form ]
Pale-yellow solid | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
Nemadipine-A is a cell permeable L-type calcium channel protein inhibitor. | [Definition]
ChEBI:Nemadipine-A is a dihydropyridine that is that is 1,4-dihydropyridine which is substituted at positions 2 and 6 by methyl groups, at positions 3 and 5 by ethoxycarbonyl groups, and at position 4 by a pentafluorophenyl group. An L-type calcium channel alpha1-subunit antagonist. When exposed to the microscopic soil nematode Caenorhabditis elegans, nemadipine-A induces a variety of defects including those affecting morphology and egg laying. It has a role as a calcium channel blocker. It is a dihydropyridine, a diester, a member of pentafluorobenzenes, an ethyl ester and a member of dicarboxylic acids and O-substituted derivatives. | [storage]
Store at -20°C |
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