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ChemicalBook--->CAS DataBase List--->528583-91-7

528583-91-7

528583-91-7 Structure

528583-91-7 Structure
IdentificationBack Directory
[Name]

7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID
[CAS]

528583-91-7
[Synonyms]

17(R)-RVD1
17(R)-RESOLVIN D1
OIWTWACQMDFHJG-BJEBZIPWSA-N
7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID
4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, (4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-
[Molecular Formula]

C22H32O5
[MDL Number]

MFCD11976905
[MOL File]

528583-91-7.mol
[Molecular Weight]

376.49
Chemical PropertiesBack Directory
[Boiling point ]

609.2±55.0 °C(Predicted)
[density ]

1.101±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -80°C
[solubility ]

DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml
[pka]

4.58±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02
[Signal word ]

Danger
[Hazard statements ]

H225
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Uses]

17(R)-Resolvin D1 is an exhibitor of a dose-dependent reduction in leukocyte infiltration.is used in methods for predicting patient response to disease-modifying antirheumatic drug (DMARD).
[Definition]

ChEBI: Aspirin-triggered resolvin D1 is a member of the class of resolvins that consists of docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid carrying three hydroxy substituents at positions 7, 8, and 17 (the 7S,8R,17S-stereoisomer). It has a role as an anti-inflammatory agent, an antiviral agent, an analgesic, a TGFbeta receptor antagonist, a nephroprotective agent, an anti-allergic agent and a human xenobiotic metabolite. It is a resolvin, a secondary allylic alcohol and a hydroxy polyunsaturated fatty acid.
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