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ChemicalBook--->CAS DataBase List--->52794-97-5

52794-97-5

52794-97-5 Structure

52794-97-5 Structure
IdentificationBack Directory
[Name]

Carubicin
[CAS]

52794-97-5
[Synonyms]

Nsc275649
Carubicin HCl
Caminomycin hydrochloride
Carminomycin hydrochloride
Karminomycin hydrochloride
4-Demethyl daunorubicin hydrochloride
5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, hydrochloride (8S-cis)-
5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, hydrochloride, (8S-cis)-
[Molecular Formula]

C26H28ClNO10
[MDL Number]

MFCD01716631
[MOL File]

52794-97-5.mol
[Molecular Weight]

549.96
Chemical PropertiesBack Directory
[alpha ]

D20 +289°
[storage temp. ]

4°C, away from moisture
[solubility ]

DMSO : 62.5 mg/mL (113.65 mM; Need ultrasonic)
[form ]

Solid
[pka]

pKa1 8.00; pKa2 10.16(at 25℃)
[color ]

Light Red to Red
Hazard InformationBack Directory
[Uses]

Antineoplastic. .
[Uses]

Karminomycin Hydrochloride is an antibiotic that potently kills human tumor cells and their multidrug resistant variants. Highly active quinone-containing anticancer drugs. A new anthracycline antineoplastic antibiotic.
Safety DataBack Directory
[Toxicity]

LD50 in mice (mg/kg): 7.3 orally; 1.3 i.v.; 3.7 s.c. (Goldberg)
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