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ChemicalBook--->CAS DataBase List--->5221-53-4

5221-53-4

5221-53-4 Structure

5221-53-4 Structure
IdentificationBack Directory
[Name]

DIMETHIRIMOL
[CAS]

5221-53-4
[EINECS(EC#)]

226-021-7
[Molecular Formula]

C11H19N3O
[MDL Number]

MFCD00129666
[MOL File]

5221-53-4.mol
[Molecular Weight]

209.29
Chemical PropertiesBack Directory
[Melting point ]

103℃
[Boiling point ]

348.66°C (rough estimate)
[density ]

1.0465 (rough estimate)
[vapor pressure ]

1.5 x 10-3 Pa at 30 °C
[refractive index ]

1.5700 (estimate)
[storage temp. ]

0-6°C
[pka]

5
[Water Solubility ]

1.2 g l-1 (25 °C)
[EPA Substance Registry System]

Dimethirimol (5221-53-4)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

21-52
[Safety Statements ]

36/37
[Toxicity]

LD50 in female rats (mg/kg): 200-400 i.p., >4000 orally (Elias)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Methanol-->Sodium-->1-Bromobutane-->1,1-DIMETHYLGUANIDINE SULFATE-->Ethyl 2-acetylhexanoate-->O-METHYLISOUREA SULFATE-->Guanidine, N,N-dimethyl-, sulfate (1:1)-->Hexanoic acid, 2-acetyl-, methyl ester
Hazard InformationBack Directory
[Uses]

Dimethirimol is a systemic fungicide that provides both protective and curative control of powdery mildew (Sphaeratheca fulginea) in cucurbits. Other uses include tobacco, tomatoes and ornamentals.
[Uses]

Fungicide.
[Definition]

ChEBI: A member of the class of aminopyrimidines that is 2-dimethylaminopyrimidine carrying methyl, butyl and hydroxy substituents at posiitons 4, 5 and 6 respectively. A fungicide first marketed in 1970, and used particularly in glasshouses to control powdery mi dew, it is no longer approved for use within the European Union.
[Metabolic pathway]

Information presented in this summary is abstracted from unpublished data in the 1971 ICI dimethirimol petition submitted to the Canadian authority. Dimethirimol is rapidly metabolised in both plants and animals. Primary metabolic reactions in soils, plants and animals are N-dealkylation, hydroxylation of the butyl group and the direct conjugation of dimethirimol in plants (glucosides) and animals (glucuronides). Metabolic pathways are shown in Scheme 1.
[Degradation]

Dimethirimol (1) is stable to heat and in acid and alkahe solutions. It is decomposed rather rapidly in aqueous solution when exposed to sunlight with an observed DT50 of 7 days.
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