Identification | Back Directory | [Name]
HYDROQUININE | [CAS]
522-66-7 | [Synonyms]
NSC 41799 HYDROQUININE 10,11-Dihydroquinine Quinine EP Impurity C Dihydroquinine,99%d.e. Quinine, 10,11-dihydro- Hydroquinine,Dihydroquinine Quinine Sulphate EP Impurity C HYDROQUININE ISO 9001:2015 REACH (8S,9R)-6'-Methoxy-10,11-dihydrocinchonan-9-ol (8α,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol (8α,9R)-6'-Methoxy-10,11-dihydrocinchonan-9-ol Cinchonan-9-ol,10,11-dihydro-6'-methoxy-, (8a,9R)- Cinchonan-9-ol, 10,11-dihydro-6'-Methoxy-, (8α,9R)- (8α,?9R)?-10,?11-Dihydro-?6'-?methoxycinchonan-?9-?ol Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (8alpha,9R)- (1R)-((2S,4S,5R)-5-Ethylquinuclidin-2-yl)(6-Methoxyquinolin-4-yl)Methanol (R)-{5-ethyl-1-azabicyclo[2.2.2]octan-2-yl}(6-Methoxyquinolin-4-yl)Methanol Dihydroquinine (R)-((1S,2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol | [EINECS(EC#)]
208-334-0 | [Molecular Formula]
C20H26N2O2 | [MDL Number]
MFCD00151107 | [MOL File]
522-66-7.mol | [Molecular Weight]
326.44 |
Chemical Properties | Back Directory | [Melting point ]
168-176 °C(lit.)
| [alpha ]
D18 -142° (alc); D20 -236° (c = 0.82 in 0.1N H2SO4) | [Boiling point ]
464.47°C (rough estimate) | [density ]
1.1117 (rough estimate) | [refractive index ]
1.6800 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly) | [form ]
Solid | [pka]
5.33(at 25℃) | [color ]
White to Off-White | [optical activity]
[α]25/D 148°, c = 1 in ethanol | [Water Solubility ]
99.99mg/L(20 ºC) | [Merck ]
13,4832 | [BRN ]
91444 | [InChIKey]
LJOQGZACKSYWCH-WGFDLZGGSA-N | [LogP]
3.770 (est) |
Hazard Information | Back Directory | [Chemical Properties]
Solid | [Uses]
(-)-Dihydroquinine, is a dihydro derivative of Quinine (Q694000), having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties. | [Definition]
ChEBI: Hydroquinine is a cinchona alkaloid. | [storage]
4°C, protect from light, stored under nitrogen | [Purification Methods]
Hydroquinine [522-66-7] M 326.4, m 168-171o, 171.5o, [ ] D-143o (c 1.087, EtOH), 5.33 and 8.87. Recrystallise hydroquinine from EtOH, Et2O or *C6H6. [Rabe & Schultz Chem Ber 66 120 1933, Beilstein 23 III/IV 3193, 23/13 V 340.] |
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