| Identification | Back Directory | [Name]
7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE | [CAS]
52029-86-4 | [Synonyms]
STO-609
STO-609, >98%
STO609;STO 609
STO-609 ACETATE
STO-609 free base
STO-609 ACETIC ACID
STO-609 - CAS 52029-86-4 - Calbiochem
7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid
7H-Benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, 7-oxo-
7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE
7H-BENZ[DE]BENZIMIDAZO[2,1-A]ISOQUINOLINE-7-ONE-3-CARBOXYLIC ACID, ACETATE
7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid - acetic acid | [Molecular Formula]
C19H10N2O3 | [MDL Number]
MFCD06411456 | [MOL File]
52029-86-4.mol | [Molecular Weight]
314.29 |
| Chemical Properties | Back Directory | [Melting point ]
>300 °C
| [Boiling point ]
716.9±62.0 °C(Predicted) | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO: 15 mg/mL at ≥60 °C
| [form ]
solid
| [pka]
2.65±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid is a calcium/calmodulin-dependent protein kinase inhibitor and was found to upregulate various AhR target genes in human macrophages. | [Definition]
ChEBI: LSM-3164 is a naphthoic acid. | [Biological Activity]
Selective, cell-permeable inhibitor of Ca 2+ -calmodulin-dependent protein kinase kinase (K i values are 80 and 15 ng/ml for inhibition of CaM-KK α and CaM-KK β respectively); competes for the ATP-binding site. Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. |
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