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ChemicalBook--->CAS DataBase List--->51765-51-6

51765-51-6

51765-51-6 Structure

51765-51-6 Structure
IdentificationBack Directory
[Name]

(2-PHENOXY)METHYLSULFONYLANILINE
[CAS]

51765-51-6
[Synonyms]

Einecs 257-399-1
Nimesulide impurity-B(EP/BP)
2-PHENOXYMETHANESULFOANILIDE
2-Phenoxymethanesulfonailide
2-PHENOXYMETHANESULFONANILIDE
(2-PHENOXY)METHYLSULFONYLANILINE
N-(2-Phenoxyphenyl)methanesulphonam
2 - phenoxy-methane-sulfonyl aniline
N-(2-phenoxyphenyl)methanesulphonamide
Methanesulfonamide, N-(2-phenoxyphenyl)-
Nimesulide EP Impurity B,(N-(2-phenoxyphenyl)methanesulfonamide)
[EINECS(EC#)]

257-399-1
[Molecular Formula]

C13H13NO3S
[MDL Number]

MFCD03389778
[MOL File]

51765-51-6.mol
[Molecular Weight]

263.31
Chemical PropertiesBack Directory
[Melting point ]

126℃
[Boiling point ]

378.9±44.0 °C(Predicted)
[density ]

1.313
[vapor pressure ]

0Pa at 25℃
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

Chloroform (Slightly), DMSO
[form ]

Solid
[pka]

8.43±0.10(Predicted)
[color ]

White to Off-White
[Water Solubility ]

176.1mg/L at 25℃
[LogP]

2.4 at 25℃
Hazard InformationBack Directory
[Uses]

2''-Phenoxymethanesulfonanilide is a metabolite of nimesulide (N477500), which is an antiinflammatory agent. It preferentially inhibits COX-2 over COX-1 and suppresses chemical-induced carcinogenesis in mice and rats. Nimesulide also nhibits LPS-induced TNF-alpha production.
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