Identification | Back Directory | [Name]
ALPHA-CORTOLONE | [CAS]
516-42-7 | [Synonyms]
CORTOLONE α-Cortolone α-Cortolone-d5 ALPHA-CORTOLONE Alpha Cortolone D5 A-cortolone crystalline 5β-Pregnane-3α,17α,20α,21-tetrol-11-one 5β-Pregnan-3α, 17, 20α, 21-Tetrol-11-One 3α,17α,20α,21-Tetrahydroxy-5β-pregnan-11-one (20S)-3α,17,20,21-Tetrahydroxy-5β-pregnan-11-one 5-BETA-PREGNAN-3-ALPHA, 17,20-ALPHA, 21-TETROL-11-ONE 5BETA-PREGNAN-3ALPHA,17ALPHA,20ALPHA,21-TETROL-11-ONE 3-ALPHA,17-ALPHA,20-ALPHA,21-TETRAHYDROXY-5-BETA-PREGNAN-11-ONE (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one | [Molecular Formula]
C21H34O5 | [MDL Number]
MFCD00056388 | [MOL File]
516-42-7.mol | [Molecular Weight]
366.49 |
Chemical Properties | Back Directory | [Melting point ]
208-209° | [alpha ]
D25 +44° (c = 0.5 in ethanol); D28 +34.2° (ethanol) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
Hazard Information | Back Directory | [Uses]
α-Cortolone is a human urinary metabolite of Cortisol ((H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. | [Definition]
ChEBI: Cortolone is a 21-hydroxy steroid. |
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