| Identification | Back Directory | [Name]
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT | [CAS]
51239-26-0 | [Synonyms]
pCPT-cGMP
8-PCPT-CGMP NA
8-PCPT-CGMP TEA
CGMP, 8-PCPT-, NA
8-PCPT-CGMP SODIUM SALT
8-pCPT-cGMP, pCPT-cGMP
8-(4-Chlorophenylthio)guanosine3&rsquo
8-(4-chlorophenylthio)guanosine*3’:5’-cyclicmono
8-(4-CHLOROPHENYLTHIO)GUANOSINE3':5'-CYC LIC MONOPH
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3':5'-CYLIC MONOPHOSPHATE SODIUM SALT
8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
8-(4-Chlorophenylthio)-guanosine-3'',5''-cyclic monophosphoric acid sodium sa
8-(4-chlorophenylthio)guanosine-3’,5’-cyclicmonophosphate(8-pcpt-cgmp),sodiumsalt | [Molecular Formula]
C16H14ClN5NaO7PS | [MDL Number]
MFCD00674888 | [MOL File]
51239-26-0.mol | [Molecular Weight]
509.79 |
| Hazard Information | Back Directory | [Uses]
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt has been used to activate GMP-dependent protein kinase (PKG) in vascular smooth muscle cells (VSMCs). | [Definition]
ChEBI: 8-(4-chlorophenylthio)-cGMP.Na is an organic sodium salt that is the monosodium salt of 8-(4-chlorophenylthio)-cGMP. It has a role as a protein kinase agonist. It contains an 8-(4-chlorophenylthio)-cGMP(1-). | [Biochem/physiol Actions]
Membrane-permeable analog of cGMP that does not affect cGMP-regulated phosphodiesterase. A more potent cGMP analog than 8-Br-cGMP due to greater membrane permeability and a higher resistance to hydrolysis by phosphodiesterase. Used as a selective activator of cGMP dependent protein kinase (PKG). Found to be a very potent cyclic nucleotide-gated channel agonist. |
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