| Identification | Back Directory | [Name]
PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 | [CAS]
51230-19-4 | [Synonyms]
TAP 142
wy-18186
(D-ALA6)-LHRH
(D-ALA8) LHRH
(d-ala(sup6))-lhrh
[D-ALA6]-LH-RH (HUMAN)
[d-ala6]-lh-rh acetate hydrate
(D-Ala6)-GnRH, (D-Ala6)-Gonadorelin
[D-Ala6]-LH-RH acetate salt hydrate
[D-Ala6]-LH-RH hydrate acetate salt
(D-ALA6)-GONADOTROPIN-RELEASING HORMONE
(D-ALA6)-LUTEINIZING HORMONE-RELEASING FACTOR
GLP-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2
(D-ALA6)-LUTEINIZING HORMONE-RELEASING HORMONE
(d-ala(sup6))-luteinizinghormone-releasinghormon
(d-ala(sup6))-luteinizinghormone-releasinghormone
PYROGLU-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY NH2
(D-Ala6)-LHRH
(D-Ala6)-GnRH, (D-Ala6)-Gonadorelin
[D-ALA6]-LUTEINIZING HORMONE-RELEASING HORMONE (HUMAN)
Luteinizing hormone-releasing factor (swine), 6-D-alanine-
(D-Ala6)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 acetate salt | [Molecular Formula]
C56H77N17O13 | [MDL Number]
MFCD00133502 | [MOL File]
51230-19-4.mol | [Molecular Weight]
1196.32 |
| Hazard Information | Back Directory | [Uses]
[D-Ala6]-LH-RH acetate salt hydrate has been used to induce ovulation and to synchronize the reproductive cycle in Sprague-Dawley female rats. | [Biochem/physiol Actions]
(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. | [in vivo]
[D-Ala6]-LH-RH (100 ng, subcutaneous injection) stimulates serum LH and FSH concentrations in immature male rats[1].
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