| Identification | Back Directory | [Name]
8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE | [CAS]
51116-01-9 | [Synonyms]
BR-CGMP, NA
8-BR-CGMP NA
8-BROMO-CGMP NA
Einecs 256-993-8
8-BROMO-CGMP SODIUM
8-BR-CGMP SODIUM SALT
(115974-70-4) 8-AET-cGMP
8-BROMO-CGMP, SODIUM SALT
8-bromo-Cyclic GMP (sodium salt)
8-BROMOGUANOSINE-3',5'-CYCLOPHOSPHATE SODIUM
8-BROMO-CGMP SODIUM SALT 8-BROMOGUANOSIN E-3',5
8-bromoguanosine 3:5-cyclic*monophosphate sodiu
8-BROMOGUANOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT
8-BROMOGUANOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM
8-Bromoguanosine-3,5-cyclomonophosphate sodium salt
8-BROMOGUANOSINE CYCLIC 3',5'-MONOPHOSPHATE SODIUM SALT
8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-BROMO-, SODIUM SALT
8-BROMOGUANOSINE-3,5-CYCLICMONOPHOSPHATESODIUMSALT,ULTRAPURE
8-bromoguanosine-3’,5’-cyclicmonophosphate(8-br-cgmp),sodiumsalt,
8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE
Guanosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), monosodium salt
Guanosine 3,5-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 51116-01-9 - Calbiochem | [EINECS(EC#)]
256-993-8 | [Molecular Formula]
C10H10BrN5O7P.Na | [MDL Number]
MFCD03703483 | [MOL File]
51116-01-9.mol | [Molecular Weight]
446.08 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
H2O: 100 mg/mL
| [form ]
powder
| [color ]
White to off-white | [Water Solubility ]
Soluble to 100 mM in water |
| Hazard Information | Back Directory | [Description]
8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 μM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations. | [Chemical Properties]
White powder | [Uses]
8-bromo-cGMP activates cGMP-dependent protein kinase. It can also inhibit acetylcholine-induced increases in intracellular calcium concentrations. | [Definition]
ChEBI: Sodium 8-bromo-3',5'-cyclic GMP is an organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. It has a role as a protein kinase G agonist and a muscle relaxant. It contains an 8-bromo-3',5'-cyclic GMP(1-). | [Biological Activity]
Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1 α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro . | [storage]
Desiccate at -20°C |
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