| Identification | Back Directory | [Name]
ETAZOLATE | [CAS]
51022-77-6 | [Synonyms]
SQ 20009
SQ 64442
ETAZOLATE
Zinc00001379
ETAZOLATE HYDROCHLORIDE
1-Ethyl-4-[2-(1-Methylethylidene)hydrazinyl]-
1-Ethyl-4-isopropylidenehydrazino-1H-pyrazolo[3,4-b]-1-pyridine-5-carboxylic Acid Ethyl Ester
1-Ethyl-4-(2-isopropylidenehydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
1-Ethyl-4-isopropylidenehydrazino- 1H-pyrazolo[3,4-β]-1-pyridine-5-carboxylic Acid Ethyl Ester
1-Ethyl-4-[2-(1-methylethylidene)hydrazinyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic Acid Ethyl Ester
1-Ethyl-4-[2-(1-methylethylidene)hydrazinyl]-1H-pyrazolo[3,4-β]pyridine-5-carboxylic Acid Ethyl Ester
1-ETHYL-4-[(1-METHYLETHYLIDENE)HYDRAZINO]-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID ETHYL ESTER, HCL
1-ETHYL-4-[(1-METHYLETHYLIDENE)HYDRAZINO]-1H-PYRAZOLO-[3,4-B]-PYRIDINE-5-CARBOXYLIC ACID, ETHYL ESTER HYDROCHLORIDE | [Molecular Formula]
C14H19N5O2 | [MDL Number]
MFCD00600136 | [MOL File]
51022-77-6.mol | [Molecular Weight]
289.33 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
193-194°C | [Boiling point ]
427.6±55.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
H2O: >20 mg/mL Solutions should be freshly prepared.
| [form ]
solid
| [pka]
9.94±0.70(Predicted) | [color ]
white
| [CAS DataBase Reference]
51022-77-6 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
An inhibitor of phosphodiesterase IV, about 8 times more active for cAMP than cGMP | [Uses]
PDE inhibitor | [Biological Activity]
Phosphodiesterase inhibitor, selective for PDE4 (IC 50 = 2.0 μ M). | [Definition]
ChEBI:Etazolate is a pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties. It has a role as a neuroprotective agent, an antipsychotic agent, a phosphodiesterase IV inhibitor, an anxiolytic drug, an antidepressant, an alpha-secretase activator and a GABA agent. It is a hydrazone, an ethyl ester and a pyrazolopyridine. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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