Identification | Back Directory | [Name]
m-PEG3-Tos | [CAS]
50586-80-6 | [Synonyms]
m-PEG3-Tos m-PEG2-Tos mPEG2-Tosylate MPEG3-TOSYLATE m-dPEG??-tosylate MeO(CH2)2O(CH2)2OTs Ethanol, 2-(2-methoxyethoxy)-, 4-methylbenzenesulfonate Ethanol, 2-(2-methoxyethoxy)-, 1-(4-methylbenzenesulfonate) | [Molecular Formula]
C12H18O5S | [MDL Number]
MFCD13184964 | [MOL File]
50586-80-6.mol | [Molecular Weight]
274.33 |
Hazard Information | Back Directory | [Description]
m-PEG3-Tos is a PEG linker containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Biological Activity]
m-PEG2-Tos is a non-cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs). It can also be used as a PROTAC linker for PROTAC synthesis. . | [in vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | [target]
Non-cleavable < span> | PEGs | |
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