Identification | Back Directory | [Name]
Oxyphenonium bromide | [CAS]
50-10-2 | [Synonyms]
c5473 ba-5473 antrenil antrenyl oxifenon oxyfenon oxyphenon Spasmophen Oxyphenonium OrpheuM broMide antrenylbromide OXYDIANIL YELLOW OXYPHENONIUM BROMIDE 2-DIETHYLAMINOETHYL-A-CYCLOHEXYL-A-PHENYLGLYCOLATE METHOBROMIDE 2-(α-cyclohexylmandeloyloxy)ethyldiethyl(methyl)ammonium bromide 2-(alpha-cyclohexylmandeloyloxy)ethyldiethyl(methyl)ammonium bromide 2-((cyclohexylhydroxyphenylacetyl)oxy)-n,n-diethyl-n-methyl-ethanaminiub DIETHYL(2-HYDROXYETHYL)METHYLAMMONIUM 2-PHENYLCYCLOHEXANEGLYCOLATE BROMIDE diethyl(2-hydroxyethyl)methylammoniumbromidealpha-phenylcyclohexaneglycolat ammonium,diethyl(2-hydroxyethyl)methyl-,bromide,alpha-phenylcyclohexaneglyco 2-(2-Cyclohexyl-2-hydroxy-2-phenylacetyl)oxyethyldiethylmethylazanium bromide 2-[(CYCLOHEXYLHYDROXYPHENYLACETYL)OXY]-N,N-DIETHYL-N-ETHYLETHANAMINIUM BROMIDE 2-[(CYCLOHEXYLHYDROXYPHENYLACETYL)-OXY]-N,N-DIETHYL-N-METHYLETHANAMINIUM BROMIDE 2-[(Cyclohexylhydroxyphenylacetyl)oxy]-N,N,-diethyl-N-methylethylammonium bromide | [EINECS(EC#)]
200-010-7 | [Molecular Formula]
C21H34BrNO3 | [MDL Number]
MFCD00050259 | [MOL File]
50-10-2.mol | [Molecular Weight]
428.4 |
Chemical Properties | Back Directory | [Melting point ]
189-194° from ethyl acetate + alc | [density ]
1.2584 (rough estimate) | [refractive index ]
1.6200 (estimate) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
A solid | [color ]
White to Off-White |
Hazard Information | Back Directory | [Uses]
anticholinergic, anticonvulsant | [Originator]
A-Spasm ,Acme Laboratories Ltd. | [Manufacturing Process]
1 mol cycloxehylhydroxyphenylacetic acid methyl ester was mixed with 1 mol 2-diethylaminoethanol in presence of 1 mol sodium methylate to give cycloxehylhydroxyphenylacetic acid 2-diethylamino-ethyl ester.
5 parts by weight of it was dissolved in 50 volumes glacial acetic acid and a gaseous methyl bromide was introduced. The mixture was heated to about 50°C and crystallization of cycloxehylhydroxyphenylacetic acid diethylaminoethyl ester methyl bromide has shortly after begun. On cooling the crystals was filtered off and recrystallized from mixture of ethyl acetate ant a little ethanol to give the oxyphenonium bromide. MP: 189°-191°C.
| [Brand name]
Antrenyl (Novartis). | [Therapeutic Function]
Anticholinergic, Spasmolytic | [Safety Profile]
Poison by ingestion, intramuscular, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: change in heart rate. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Brí. |
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