Identification | Back Directory | [Name]
5-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)imidazolidine-2,4-dione | [CAS]
484049-04-9 | [Synonyms]
104868 DPH >=98% (HPLC) 5-(1,3-diaryl-1H-pyrazol-4-yl)hydantoin 5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-2,4-imidazolidinedione 5-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)imidazolidine-2,4-dione 2,4-Imidazolidinedione, 5-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]- | [Molecular Formula]
C18H13FN4O2 | [MDL Number]
MFCD03268950 | [MOL File]
484049-04-9.mol | [Molecular Weight]
336.32 |
Hazard Information | Back Directory | [Uses]
DPH may be used in c-Abl tyrosine kinase-mediated cell signaling studies. | [Biochem/physiol Actions]
DPH is a potent cell permeable c-Abl activator. DPH binds to the myristoyl binding site and leads to activation of c-Abl kinase activity. The compound stimulates the phosphorylation of c-Abl and its downstream substrate Crk. |
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