| Identification | Back Directory | [Name]
CORYNANTHINE | [CAS]
483-10-3 | [Synonyms]
Nsc407306
Rauhimbin
RAUHIMBINE
Corynanthin
Coynanthine
CORYNANTHINE
CORYNANTHINE HCL(RG)
CORYNANTHINE DIHYDRATE
corynanthine free base
methyl (16beta,17alpha)-17-hydroxyyohimban-16-carboxylate
17ALPHA-HYDROXYYOHIMBAN-16BETA-CARBOXYLIC ACID METHYL ESTER
Yohimban-16.beta.-carboxylic acid, 17.alpha.-hydroxy-, methyl ester
Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16.beta.,17.alpha.)- | [EINECS(EC#)]
207-590-0 | [Molecular Formula]
C21H26N2O3 | [MDL Number]
MFCD00069659 | [MOL File]
483-10-3.mol | [Molecular Weight]
354.44 |
| Hazard Information | Back Directory | [Description]
This alkaloid has been isolated by Hoffmann from the bark of Rauwolfia
serpentina. It forms colourless crystals from Me2CO and has [α]20D - 82° (c 0.5,
pyridine). | [Uses]
Corynanthine is a selective α1-adrenergic receptor antagonist. Corynanthine can significantly lower intraocular pressure in rabbits[1]. | [Definition]
ChEBI:Corynanthine is a yohimban alkaloid. | [References]
Hoffmann., Helv. Chim. Acta, 37,314,849 (1954) |
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